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Urine drug testing process is an important step in screening drug users. To ensure that the test results are precise, accurate and reliable, it is therefore necessary that the laboratories testing should participate in the proficiency testing program with the certified unit according to ISO / IEC 17043: 2010. Bureau of Drugs and Narcotics, Department of Medical Sciences has been aunit of proficiency testing provider for narcotics in urine since the fiscal year 2003 until the present. The proficiency testing for narcotics in urine consists of two schemes, namely, scheme of screening test of narcotics in urine and confirmation testing of narcotics in urine.There are a number of participating laboratories in both the public and private sectors increased by 766 respectively in the fiscal year 2018. The prevalent narcotics, methamphetamine, morphine, marijuana, ecstasy and cocaine, were used as proficiency test samples four samples a year.Because of training courses and supervision the participating laboratories of us every year, the participants reported the accurate results increasing more than 90 percent in 2018. However, there are some members reported with the inaccurate test results therefore we will plan to develop such members further. Moreover, to meet the needs of members effectively, we have used information technology. Participants are satisfied with the service. Participants’ clientreceives fairness and increase the effectiveness of prevention and suppression of drug abuse in the country